Le magazine américain EW (Entertainement Weekly) a annoncé les artistes présents dans le jeu DJ Hero 2 sur PS3, Wii et X360 :

* 2Pac
* 50 Cent
* Adamski
* Afrika Bambaataa & The Soul Sonic Force
* Armand Van Helden
* A-Trak
* B.o.B.
* Basement Jaxx
* BlakRoc
* Bobby Womack
* Bruno Mars
* Busta Rhymes
* Calvin Harris
* Chamillionaire
* Chic
* Chris Willis
* Clinton Sparks
* Colby O’Donis
* Daft Punk
* Damian Marley
* David Guetta
* Deadmau5
* Deee-Lite
* Dillinja
* Diplo
* Dizzee Rascal
* DJ Shadow
* Donna Summer
* Dr. Dre
* Drake
* Edwin Starr
* Eminem
* Estelle
* Flo Rida
* Gorillaz
* Grandmaster Flash & The Furious Five
* Harold Faltermeyer
* House Of Pain
* Iyaz
* Jackson 5
* Janet Jackson
* Justice
* Kanye West
* Kaskade
* Kelis
* Keri Hilson
* Kid Cudi
* Kool & The Gang
* Lady Gaga
* Lil Jon
* Lil Wayne
* LL Cool J
* M.I.A.
* M|A|R|R|S
* Major Lazer
* Malcolm McLaren
* Mase
* Melle Mel & Duke Bootee
* Metallica
* Missy Elliott
* Mos Def
* MSTRKRFT
* N.O.R.E.
* Nas
* Nate Dogg
* Naughty By Nature
* Nelly
* New Boyz
* New Order
* Newcleus
* Nightcrawlers
* Orbital
* Pharoahe Monch
* Pirate Soundsystem
* Pitbull
* Puff Daddy
* Pussycat Dolls
* Rihanna
* Robin S.
* RZA
* Salt N Pepa
* Sam Cooke
* Sam Sparro
* Sean Paul
* Skibadee
* Sneaky Sound System
* Snoop Dogg
* Snow
* Soulja Boy Tell Em
* Sparfunk & D-Code
* Static Major
* Stevie Wonder
* Talib Kweli
* The Chemical Brothers
* The Crystal Method
* The Egg
* The Notorious B.I.G.
* The Prodigy
* Tiësto
* Tiga
* Timbaland
* Tweet
* Walter Murphy
* Warren G
* Wayne Smith
* Will.I.Am
* Yeah Yeah Yeahs
* Young Jeezy